Steroid administration

Anabolic / androgenic steroids are not medically approved to promote excessive muscle mass gains (bodybuilding) or improve athletic performance. There is a large variety of different approaches to using these agents, some safer or more effective than others. This section will discuss some of the most fundamental and time-proven methods for using AAS.

Acquiring AAS (Best Practices)

This section assumes that the decision has already been made to use anabolic steroids. It places no judgment on the decision itself, and concentrates only on reducing risks relating to the drug supply. How one goes about obtaining these substances is an extremely important consideration. Much more...

Acute Steroid Safety: Studies with Real-World Dosages

Few medicines have the type of stigma about them that anabolic/androgenic steroids do. If you mention the decision to use these drugs to the average person, you are likely to be lectured about the tremendous physical and psychological risks you are about to undertake; how your hair might fall out,...

Anabolic Steroids and the Law

United States law prohibits the possession of anabolic steroids without a legal medical prescription, imparting severe penalties (including fine and/or imprisonment) for those that choose to violate these laws. Under influence of U.S. government officials, World Anti- Doping Agency (WADA) members,...

Brief History of Anabolic / Androgenic Steroids

While it had been clear for many centuries that the testicles were crucial for the male body to properly develop, it was not until modern times that an understanding of testosterone began to form. The first solid scientific experiments in this area, which eventually led to the discovery and...

Clinical Applications

Anabolic/androgenic steroids are approved for sale by prescription in virtually every pharmaceutical market around the world. Having been applied for many decades to treat a variety of diseased states, today these drugs have a number of well-established medical uses. They have been used to treat...

Counterfeit Steroid Identification

This section pertains to methods for differentiating between legitimate pharmaceutical products and illegitimate copies (counterfeits). Before we begin, I need to remind you that counterfeiting anabolic steroids is a very lucrative business these days. Counterfeiters are investing a lot of money in...

Counterfeit Steroids

As the name implies, counterfeit steroids are copies of real anabolic/androgenic steroid products, which are made from illicit producers. These drugs are intended for sale on the black market, ultimately to consumers who believe they are buying a legitimate pharmaceutical item from the labeled...

Country Specifics

In most countries, a pharmaceutical company is required to meet a specific set of regulations pertaining to the physical packaging of a pharmaceutical product. In some cases these regulations can be used to help evaluate the legitimacy of black market steroids, as all counterfeiters may not have the...

Designer Steroids

There is a fatal flaw in the steroid detection methods used by the various sports agencies. That is, in order to test someone for anabolic steroids, you need to know exactly what you are looking for. You can’t just look for “steroids” in the urine, but are forced to test for each specific...

DHT Conversion

As we see from our discussion with estrogen, in considering the physiological effects of any steroid, we must look at all of its active metabolites, and not just the initial compound. This includes not only estrogenic products, but androgenic metabolites as well. With this in mind, it is important...

Direct and Indirect Anabolic Effects

Although testosterone has been isolated, synthesized, and actively experimented with for many decades now, there is still some debate today as to exactly how steroids affect muscle mass. At this point in time, the primary mode of anabolic action with all anabolic/androgenic steroids is understood to...

Estrogen Aromatization

Testosterone is the primary substrate used in the male body for the synthesis of estrogen (estradiol), the principal female sex hormone. Although the presence of estrogen may seem quite unusual in men, it is structurally very similar to testosterone. With a slight alteration by the enzyme aromatase,...

Free vs. Bound Testosterone

A very small amount of testosterone actually exists in a free state, where interaction with cellular receptors is possible. The majority will be bound to the proteins SHBG (sex hormone binding globulin, also referred to as sex steroid binding globulin and testosterone-estradiol binding globulin) and...

Harm Reduction / Safer Use Guidelines

Harm reduction is a concept among healthcare workers that seeks to reduce the negative health consequences of drug abuse. The principles of harm reduction call for an acceptance of the fact that, good or bad, illicit drugs exist in today’s society. Instead of ignoring drug users, harm reduction...

Injection Protocols

Anabolic/androgenic steroid injections are always given deep in the muscle (intramuscular). Some other performance-enhancing drugs such as human growth hormone and insulin injections are given by injection in the fat layer between the skin and muscle (subcutaneous). The protocols for both injection...

Introduction to Testosterone

Anabolic steroids are a class of medications that contain a synthetically manufactured form of the hormone testosterone, or a related compound that is derived from (or similar in structure and action to) this hormone. In order to fully grasp how anabolic steroids work, it is, therefore, important to...

OCT - Off-Cycle Therapy

The objective of anabolic steroid therapy (when nonmedical applications are involved) should be to elicit the desired benefits with the lowest cumulative exposure and side effects. This normally includes diligence with optimizing all aspects of training, rest, and diet, as well as adhering to a...

PCT - Post-Cycle Therapy

Post-Cycle Therapy, or PCT for short, refers to the practice of using certain medications to assistant in the discontinuance of anabolic steroids. While steroids are not addictive drugs in a classical sense, they do suppress your own hormone production, at least temporarily. This is an issue that...

Sample Steroid Cycles

The following cycles are presented as examples of common steroid administration protocols. These programs have not been evaluated in a clinical setting for safety and efficacy, and are provided for informational purposes only. These are not recommendations for anabolic/androgenic steroid use. As...

Sterilizing Injectable AAS

Anabolic steroid products made by licensed drug manufacturers have an expectation of sterility. This is assured by the rigid government regulations applied to these companies. Unfortunately, there is no such expectation for counterfeit and underground steroid products. Most are assembled under...

Steroid Cycles

Anabolic/androgenic steroids are not medically approved to promote excessive muscle mass gains (bodybuilding) or improve athletic performance. Aside from early experimentation on athletes by a handful of sports physicians, an extensive effort to study the physique- and performance-enhancing...

Steroid Nomenclature

Perhaps not obvious at first glance, there is a naming convention in place that was used to create identities for the various anabolic/androgenic steroid hormones. This typically involves create identities for the various anabolic/androgenic steroid hormones. This typically involves forming a root...

Synthetic AAS Chemistry

All anabolic/androgenic steroids are preparations containing one of the above three natural steroid hormones, or chemically altered derivatives thereof. In creating new synthetic compounds, one of the three natural hormones is selected as a starting point, typically due to the possession of...

Synthetic AAS Development

In order to develop products that would be effective therapeutically, chemists needed to solve a number of problems with using natural steroid hormones for treatment. For example, oral dosing was a problem, as our basic steroids testosterone, nandrolone, anddihydrotestosterone are ineffective when...

The Endocrinology of Muscle Growth

The road to anabolic insight must include a biological understanding of what muscle growth actually entails. Often simplified by the term “protein synthesis”, muscle growth is actually a highly complex process involving much more than just building proteins from amino acids. Muscle hypertrophy,...

Underground Steroids

An underground steroid is an anabolic/androgenic steroid product that was made by an illegal (underground) laboratory. These drugs are specifically manufactured for sale to athletes and bodybuilders on the black market, and are not available through legitimate channels such as pharmacies and drug...

Understanding Blood Tests

The abuse of anabolic/androgenic steroids can have a number of potential negative health consequences, most commonly with regard to cardiovascular and liver health. These issues, however, can almost always be identified in blood work well before physical symptoms become apparent. Cardiovascular...